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It appears that, if you’re a mouse, you should avoid drinking large amounts of tea.
Working with a team of graduate students, Professor Peter O’Brien of the Leslie Dan Faculty of Pharmacy injected low and concentrated doses of polyphenols into mice. At low doses, “good” polyphenols protected the liver or isolated liver cells against oxygen radicals, while “bad” polyphenols caused liver toxicity at high concentrations.
“The low concentration is roughly equivalent to what people consume when they drink green or black tea,” O’Brien says. “But the health benefits are not clear as only a small amount of the polyphenols in the teas seems to get absorbed across the intestine. We won’t know how much is absorbed or metabolized without running large clinical trials involving humans.”
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