Bangladesh reports first human case of H5N1 bird flu
Bangladesh reported its first human case of the H5N1 strain of Avian flu on Thursday. According to a representative of the Bangladesh health ministry, the 16-month old boy initially tested negative for the disease. His virus culture tested positive in tests performed by the United States Centers for Disease Control and Prevention. The boy is from the capital city of Dhaka in the Dhaka District.
“Although there is no farm in the neighborhood we suspect that he got the illness after his family bought chickens from a farm,” said senior health ministry official Mahmudur Rahman. Rahman is the head of Bangladesh’s Institute of Epidemiology and Disease Control and Research. He asserted that the government had the disease under control, and that physicians and hospitals in the country were adequately prepared.
Rahman said Thursday that the child had recovered from the disease. “The child was found infected by H5N1 but after treatment he has recovered and is now doing well,” said Rahman in a statement to Reuters.
The World Health Organization (WHO) confirmed the positive test results on Friday. This case in Bangladesh brings the total number of countries in the world with human infections from the disease up to 15. “When a disease is so widespread in poultry, it is really a matter of time before you get a human case. It shows the need to control the disease in animals if you are going to reduce the chances of transmission to humans,” said WHO spokesman Gregory Hartl in a statement to Reuters.
The boy had previously been diagnosed with H5N1 in January, but the CDC only confirmed the case this week. In a statement in Agence France-Presse, senior government official Saluddin Khan said: “There is no reason to panic. The child contracted the H5N1 bird flu virus in January but we only got confirmation from the CDC on Wednesday it was a human bird flu case.”
Khan commented on preventative measures being taken by the government, saying, “we’re destroying the birds and eggs as soon as we have any report of bird flu at any farm in the country.”
Bangladesh was first hit by bird flu in February 2007, and after a period of dormancy, was hit again in January 2008. Outbreaks subsided in March when peaking temperatures killed off the virus. Over one million birds were slaughtered during the outbreaks, and at the peak the outbreaks were the cause of a loss 1.5 million jobs in the Bangladesh poultry industry, which is the largest in the world. The Avian influenza has spread through 47 of Bangladesh’s 64 districts.
The H5N1 virus seldom infects humans, but according to WHO there have been 382 human cases globally since 2003, including 241 deaths.
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May 24th, 2008 at 11:49 pm
Spread of avian flu by drinking water:
Proved awareness to ecology and transmission is necessary to understand the spread of avian flu. For this it is insufficient exclusive to test samples from wild birds, poultry and humans for avian flu viruses. Samples from the known abiotic vehicles also have to be analysed. There are plain links between the cold, rainy seasons as well as floods and the spread of avian flu. That is just why abiotic vehicles have to be analysed. The direct biotic transmission from birds, poultry or humans to humans can not depend on the cold, rainy seasons or floods. Water is a very efficient abiotic vehicle for the spread of viruses – in particular of fecal as well as by mouth, nose and eyes excreted viruses.
Infected birds and poultry can everywhere contaminate the drinking water. All humans have very intensive contact to drinking water. Spread of avian flu by drinking water can explain small clusters in households too. Proving viruses in water is difficult because of dilution. If you find no viruses you can not be sure that there are not any. On the other hand in water viruses remain viable for a long time. Water has to be tested for influenza viruses by cell culture and in particular by the more sensitive molecular biology method PCR.
There is a widespread link between avian flu and water, e.g. in Egypt to the Nile delta or Indonesia to residential districts of less prosperous humans with backyard flocks and without central water supply as in Vietnam: http://www.cdc.gov/ncidod/EID/vol12no12/06-0829.htm. See also the WHO web side: http://www.who.int/water_sanitation_health/emerging/h5n1background.pdf .
Transmission of avian flu by direct contact to infected poultry is an unproved assumption from the WHO. There is no evidence that influenza primarily is transmitted by saliva droplets: “Transmission of influenza A in human beings†http://www.thelancet.com/journals/laninf/article/PIIS1473309907700294/abstract?iseop=true .
Avian flu infections may increase in consequence to increase of virus circulation. In hot climates/the tropics flood-related influenza is typical after extreme weather and floods. Virulence of influenza viruses depends on temperature and time. Special in cases of local water supplies with “young†and fresh H5N1 contaminated water from low local wells, cisterns, tanks, rain barrels, ponds, rivers or rice paddies this pathway can explain small clusters in households. At 24°C e.g. in the tropics the virulence of influenza viruses in water amount to 2 days. In temperate climates for “older†water from central water supplies cold water is decisive to virulence of viruses. At 7°C the virulence of influenza viruses in water amount to 14 days.
Human to human and contact transmission of influenza occur – but are overvalued immense. In the course of influenza epidemics in Germany, recognized clusters are rare, accounting for just 9 percent of cases e.g. in the 2005 season. In temperate climates the lethal H5N1 virus will be transferred to humans via cold drinking water, as with the birds in February and March 2006, strong seasonal at the time when drinking water has its temperature minimum.
The performance to eliminate viruses from the drinking water processing plants regularly does not meet the requirements of the WHO and the USA/USEPA. Conventional disinfection procedures are poor, because microorganisms in the water are not in suspension, but embedded in particles. Even ground water used for drinking water is not free from viruses.
http://www.un.org/apps/news/story.asp?NewsID=26096&Cr=&Cr1
Ducks and rice [paddies = flooded by water] major factors in bird flu outbreaks, says UN agency
Ducks and rice fields may be a critical factor in spreading H5N1
26 March 2008 – Ducks, rice [fields, paddies = flooded by water! Farmers on work drink the water from rice paddies!] and people – and not chickens – have emerged as the most significant factors in the spread of avian influenza in Thailand and Viet Nam, according to a study carried out by a group of experts from the United Nations Food and Agriculture Organization (FAO) and associated research centres.
“Mapping H5N1 highly pathogenic avian influenza risk in Southeast Asia: ducks, rice and people†also finds that these factors are probably behind persistent outbreaks in other countries such as Cambodia and Laos.
The study, which examined a series of waves of H5N1 highly pathogenic avian influenza in Thailand and Viet Nam between early 2004 and late 2005, was initiated and coordinated by FAO senior veterinary officer Jan Slingenbergh and just published in the latest issue of the Proceedings of the National Academy of Sciences of the United States.
Through the use of satellite mapping, researchers looked at a number of different factors, including the numbers of ducks, geese and chickens, human population size, rice cultivation and geography, and found a strong link between duck grazing patterns and rice cropping intensity.
In Thailand, for example, the proportion of young ducks in flocks was found to peak in September-October; these rapidly growing young ducks can therefore benefit from the peak of the rice harvest in November-December [at the beginning of the cold: Thailand, Viet Nam, Cambodia, Laos are situated – different from Indonesia – in the northern hemisphere].
“These peaks in congregation of ducks indicate periods in which there is an increase in the chances for virus release and exposure, and rice paddies often become a temporary habitat for wild bird species,†the agency said in a news release.
“We now know much better where and when to expect H5N1 flare-ups, and this helps to target prevention and control,†said Mr. Slingenbergh. “In addition, with virus persistence becoming increasingly confined to areas with intensive rice-duck agriculture in eastern and south-eastern Asia, evolution of the H5N1 virus may become easier to predict.â€
He said the findings can help better target control efforts and replace indiscriminate mass vaccination.
FAO estimates that approximately 90 per cent of the world’s more than 1 billion domestic ducks are in Asia, with about 75 per cent of that in China and Viet Nam. Thailand has about 11 million ducks.
Dipl.-Ing. Wilfried Soddemann – Epidemiologist – Free Science Journalist soddemann-aachen@t-online.de