Vitamin D, Cardiovascular Disease & Death
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By, Robert A. Wascher, MD, FACS “A critical weekly review of important new research findings for health-conscious readers” VITAMIN D, CARDIOVASCULAR DISEASE & DEATH There is mounting evidence that Vitamin D plays a much more complex role in maintaining health beyond its primary function in regulating calcium absorption. Increasingly, research data suggests that this hormone-like vitamin may also play important roles in the prevention of cardiovascular disease and cancer, as well. (A comprehensive update on Vitamin D’s cancer prevention properties will appear in my forthcoming book, “A Cancer Prevention Guide for the Human Race.”) The vast majority of published research studies in disease prevention have relied upon low-level research methods, including surveys of patient volunteers and retrospective medical chart reviews. More recently, however, high-quality prospective, randomized cardiovascular disease prevention and cancer prevention clinical research trials have been performed. These high-level studies have the potential to significantly improve lifestyle-based approaches to preventing the diseases that, together, cause the majority of all premature deaths. A newly published prospective clinical research study, from the Chianti region of Italy, enrolled more than 1,000 adults, aged 65 years and older. All patient volunteers were tested for the level of Vitamin D in their blood when they joined this study, and all of these older adults were then carefully followed for an average of nearly 7 years. During the course of this study, 228 study participants died. The researchers then compared the levels of Vitamin D in the blood of the participants who died during the study with those of the volunteers who survived. (This study is published in the current issue of the European Journal of Clinical Nutrition.) The findings of this prospective clinical study were striking. The patient volunteers with the lowest levels of Vitamin D in their blood were more than 2 times as likely to die, from any cause, when compared with the patients who had the highest levels of Vitamin D in their blood. The patients with the lowest Vitamin D levels were also nearly 3 times as likely to die from heart attacks, and other complications related to cardiovascular disease, when compared to the patients with high levels of Vitamin D in their blood. These dramatic findings held up even after the researchers made statistical adjustments for differences in the age, gender, education level, exercise habits, and other health-related factors among these two groups of study participants. As we age, our bodies become less efficient in converting sunlight into Vitamin D, and multiple research studies have shown that the majority of older adults are deficient in Vitamin D. A growing number of high-level clinical research studies, such as this Italian study, continue to suggest that Vitamin D deficiency is associated with an increased risk of cardiovascular disease, cancer, osteoporosis, bone fractures, and decreased muscle strength in older men and women. Therefore, the importance of this vitamin-hormone in maintaining optimal health is becoming increasingly apparent. For additional Weekly Health Update articles on Vitamin D, please click the following links: http://doctorwascher.com/Archives/2-3-08 http://doctorwascher.com/Archives/10-11-09.htm http://doctorwascher.com/Archives/11-8-09.html http://doctorwascher.com/Archives/9-20-09.htm http://doctorwascher.com/Archives/8-9-09.htm http://doctorwascher.com/Archives/12-28-08.htm http://doctorwascher.com/Archives/10-5-08.htm http://doctorwascher.com/Archives/6-29-08.htm In view of the extreme devastation and human misery brought about in Haiti by the recent earthquake, Weekly Health Update asks our tens of thousands of caring readers to give generously to established charities that are currently working in that country to assist the injured, the ill, and the homeless there. There are many such legitimate charities, including the following two: http://www.imcworldwide.org/haiti Disclaimer: As always, my advice to readers is to seek the advice of your physician before making any significant changes in medications, diet, or level of physical activity Dr. Wascher is an oncologic surgeon, a professor of surgery, a cancer researcher, an oncology consultant, and a widely published author For a somewhat lighter perspective on Dr. Wascher, please click on the following YouTube link: |
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Wascher, MD, FACS All rights reserved Dr. Wascher’s Archives: 1-31-2010: Concord Grape Juice Improves Memory 1-24-2010: Mozart, Music, Babies & Health 1-17-2010: Breast Cancer, Physical Therapy & Lymphedema 1-10-2010: Prevention of Surgical Site Infections (SSIs) after Surgery 1-3-2010: Ginkgo Biloba, Memory & Cognitive Health 12-20-2009: CT Scans & Cancer Risk 12-13-2009: Soy Isoflavones Decrease Breast Cancer Recurrence Risk 12-6-2009: Salt (Sodium) Intake, Stroke & Cardiovascular Disease 11-29-2009: Exercise & Prostate Cancer Risk 11-22-2009: Genistein (Soy Isoflavone) & Prostate Cancer 11-15-2009: Breast Cancer Treatment & Chronic Pain 1-8-2009: Vitamin D & Breast Cancer Risk 11-1-2009: Exercise & Prostate Cancer Risk 10-25-2009: HPV Virus & Risk of Breast Cancer 10-18-2009: Post-Cholecystectomy Syndrome (Symptoms after Gallbladder Surgery) 10-11-2009: Vitamin D & Falls in the Elderly 10-4-2009: Surgery, NSQIP, Complications & Death 9-27-2009 Stress, Heart Disease, Exercise & Death 9-20-2009: Vitamin D & Colorectal Cancer Survival 9-13-2009: H1N1 Swine Flu Update 9-7-2009: Green Tea, Aging & Lifespan 8-30-2009: Irritable Bowel Syndrome (IBS), Diet & Fiber 8-23-2009: Update on Prostate Cancer and Cryotherapy 8-16-2009: Exercise Improves Lymphedema Symptoms in Breast Cancer Survivors 8-9-2009: Breast Cancer Recurrence, Death & Vitamin D 8-2-2009: Honesty, Dishonesty & Brain Function 7-26-2009: Coronary Artery CT Scans & Cancer Risk 7-19-2009: Hormone Replacement Therapy (HRT) & Ovarian Cancer 7-12-2009: Breast Cancer & Metformin (Glucophage) 7-5-2009: Prostate Cancer & Green Tea 6-28-2009: Air Pollution & the Risk of Deep Venous Thrombosis (DVT) 6-21-2009: Red Yeast Rice, Statins & Cholesterol 6-14-2009: Bone Marrow Stem Cell Transplant & Congestive Heart Failure (CHF) 6-7-2009: Diet, Soy & Breast Cancer Risk 5-31-2009: Diet and Prostate Cancer Risk 5-24-2009: Diabetes, Glucose Control & Death 5-17-2009: Drug Company Marketing & Physician Prescribing Bias 5-10-2009: Hemorrhoids & Surgery 5-3-2009: Statin Drugs & Blood Clots (Thromboembolism) 4-26-2009: Are We Really Losing the War on Cancer? 4-19-2009: Exercise in Middle Age & Risk of Death 4-12-2009: Can Chronic Stress Harm Your Heart? 4-5-2009: Does PSA Testing for Prostate Cancer Save Lives? 3-15-2009: Depression, Stress, Anger & Heart Disease 3-8-2009: Coronary Artery Disease: CABG vs. Stents?; Swimming Lessons & Drowning Risk in Children 3-1-2009: Aspirin & Colorectal Cancer Prevention; Fish Oil & Respiratory Infections in Children 2-22-2009: Health Differences Between Americans & Europeans; Lycopene & Prostate Cancer 2-15-2009: Statin Drugs & Death Rates; Physical Activity, Breast Cancer & Sex Hormones 2-8-2009: Hormone Replacement Therapy (HRT) & Breast Cancer; Stool DNA Testing & Cancer of the Colon & Rectum 1-25-2009: Prostate Cancer, Fatigue & Exercise; Does your Surgeon “Warm-up” Before Surgery? 1-18-2009: Cancer and Vitamins; Teenagers, MySpace and Risky Behaviors 1-11-2009: Exercise Reverses Some Effects of Fatty Meals; Vitamin C and Blood Pressure 12-28-2008: Stress & Your Risk of Heart Attack; Vitamin D & the Prevention of Colon & Rectal Polyps 12-21-2008: Breast Cancer Incidence & Hormone Replacement Therapy; Circumcision & the Risk of HPV & HIV Infection 12-14-2008: Vitamin E, Vitamin C and Selenium Do Not Prevent Cancer; Postscript: A Possible Cure for Down’s Syndrome 12-7-2008: Generic vs. Brand-Name Drugs, Stress & Breast Cancer Survival 11-30-2008: A Possible Cure for Down’s Syndrome?; Smoking & Cognitive Decline; Calcium & Vitamin D & Breast Cancer Risk 11-23-2008: Breast Cancer & Fish Oil; Lymphedema after Breast Cancer Treatment; Vasectomy & Prostate Cancer Risk 11-9-2008: Statins Cut Heart Attack Risk Even with Normal Cholesterol Levels; Statins & PSA Level 11-2-2008: Radiation Treatment of Prostate Cancer & Second Cancers; Sexual Content on TV & Teen Pregnancy Risk 10-26-2008: Smoking & Quality of Life 10-19-2008: Agent Orange & Prostate Cancer 10-12-2008: Pomegranate Juice & Prostate Cancer 10-5-2008: Central Obesity & Dementia; Diet, Vitamin D, Calcium, & Colon Cancer 9-28-2008: Publication & Citation Bias in Favor of Industry-Funded Research? 9-21-2008: Does Tylenol® (Acetaminophen) Cause Asthma? 9-14-208: Arthroscopic Knee Surgery- No Better than Placebo?; A Healthy Lifestyle Prevents Stroke 8-23-2008: Alcohol Abuse Before & After Military Deployment; Running & Age; Running & Your Testicles 3-16-2008: Benefits of a Full Drug Coverage Plan for Medicare Patients?; Parent-Teen Conversations about Sex; Soy (Genistein) & Prostate Cancer 2-23-2008: Universal Healthcare Insurance Study; Glucosamine & Arthritis 2-3-2008: Vitamin D & Cardiovascular Health; Vitamin D & Breast Cancer; Green Tea & Colorectal Cancer 1-12-2008: Statins, Diabetes & Stroke and Obesity; GERD & Esophageal Cancer 12-31-2007: Minority Women, Hormone Replacement Therapy & Breast Cancer; Does Health Insurance Improve Health? 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